نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانش‌آموخته کارشناسی ارشد، گروه علوم و صنایع غذایی، دانشگاه آزاد اسلامی، واحد صفادشت، تهران، ایران
2 دانشیار، گروه علوم و صنایع غذایی، دانشگاه آزاد اسلامی، واحد صفادشت، تهران، ایران
3 دانشیار، گروه علوم و صنایع غذایی، انستیتو تحقیقات تغذیه و صنایع غذایی کشور، دانشکده علوم تغذیه و صنایع غذایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
This research aims to evaluate the antioxidant, lipase inhibitory activity, and antimicrobial properties of Capparis decidua and Withania somnifera extracts. For this purpose, the total phenolic compounds of the plant extracts were investigated by Folin-ciocalte method, and the antioxidant activity by ABTS free radical inhibition test and lipase inhibitory activity were determined. The antimicrobial properties of the extracts were also evaluated on Candida albicans, Pseudomonas aeruginosa, and Streptococcus mutans strains by well diffusion method. Also, the effect of Withania somnifera and Capparis decidua extracts on Helicobacter pylori was investigated. The results of the total phenolic content in the extracts showed a positive relationship between the phenolic compounds and the concentration of extract. The highest amount of phenolic compounds is present in the extract of Withania somnifera plant. The results of the investigation of the antioxidant property showed that there is a positive and significant relationship between the percentage of free radical inhibition and the concentration of the extracts, and Withania somnifera extract has the highest antioxidant property in the examination of the extracts. It was found that the extract of Capparis decidua (94.32%) was the most effective in inhibiting lipase enzymes. Examining the average diameter of zone of inhibition of the extracts against Pseudomonas aeruginosa, Candida albicans, and Streptococcus mutans showed that Withania somnifera extract had the largest diameter against Pseudomonas aeruginosa. Capparis decidua extract has the most antimicrobial properties against Candida albicans and also Capparis decidua extract has the highest non-growth halo against Streptococcus mutans bacteria. The minimum inhibitory concentration against Pseudomonas aeruginosa is related to Withania somnifera extract with concentration. The minimum concentration of Capparis decidua extract is against Streptococcus mutans and against Candida albicans, which has the highest antimicrobial properties compared to Withania somnifera in the minimum concentration. In the study of the effect of extracts on Helicobacter pylori, it was found that the highest Helicobacter inhibitory rate was related to Capparis decidua extract (94.32%).Therefore, the extracts of these plants can be used as natural additives.
کلیدواژه‌ها [English]
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